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In situations where abnormal signals for cell division over-rides these inhibitory steps, such as oncogenic transformation of cells, p53 mediated cell death or senescence eliminates these clones of cells resulting in benign tumors

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The DoD has the largest SBIR budget of any participating agency and has also shown considerable interest in changing its approaches to accessing new companies from outside the traditional defense industrial base through such new organizations as the Defense Innovation Unit and AFWERX